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Test Code LAB477 Levetiracetam (Keppra)

Sunquest ordering code

LEVET

PERFORMING SITE

Pathology Laboratory

SPECIMEN COLLECTION

Preferred Collection Container: Red (No Additive)

Also Acceptable Collection Container: 

Green (Lithium Heparin)
Lavender (EDTA)

Collection Information: Serum (Red top) or plasma (Green or Lavender top). For consistency, using the same specimen matrix for individual patients is a good practice.  

Gel separator tubes are NOT acceptable.

Transport Information: 3.0 mL blood

CPT Codes

80177

Minimum Volume

0.5 mL of blood (0.1 mL serum or plasma)

Specimen Stability

Refrigerated Stability: 7 days

Frozen Stability: 4 weeks

Ambient Stability: Acceptable if sample has been separated from cells.

Reject Due To

Unacceptable Conditions: Gel separator tubes.

Method

Immunoassay

This levetiracetam (Keppra) immunoassay uses the ARK Diagnostics reagents, which has known cross-reactivity with the drug brivaracetam (Briviact) and may report inaccurate results. Patients transitioning from levetiracetam to brivaracetam or those who are using both medications should not monitor drug concentrations with the ARK Diagnostics assay. These patients should be monitored using a validated chromatographic methodology that distinguishes between drugs to determine drug concentrations.

Notes

Performed: 

Monday-Friday 8:00a to 10:00p
Saturday-Sunday 9:00a to 5:00p

Analytical Time: 2 hours

Alias

Keppra