Test Code LAB352 5-Hydroxyindoleacetic Acid (HIAA), Urine
Sunquest ordering code
U5HAA
PERFORMING SITE
Pathology Laboratory
SPECIMEN COLLECTION
Container/Tube Type: 24 hour urine collection jug
Collection Information: 24-hour. 24-hour specimens should be refrigerated during collection. Random specimens can be analyzed, but reference ranges have not been established.
Transport Information: Entire Specimen
Remarks: Patients should abstain, if possible, from foods, medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test. 24-hour collections are generally recommended, but random collections may also be used. Refrigeration is the most important aspect of specimen preservation. Foods and medications that are associated with altered Urinary HIAA results: Decreased Results: Aspirin, Chlorpromazine(Thorazine), Corticotropin, Dihydroxyphenylacetic, Ethanol, Gentisic acid, Homogentisic acid, Hydrazine derivatives, Imipramine(Tofranil), Isocarboxazid(Marplan), Keto acids, Levodopa, Mao inhibitors, Methenamine, Methyldopa (Aldochlor), Phenothiazines(Compazine), Perchlorperazine, Promazine, Promethazine. Increased Results : Acetaminophen, Acetanilid, Caffeine, Coumaric acid, Ephedrine, Fluoracil, Glycerol Guaiacolate (Guaifenesin), Melphalin (Alkeran), Mephenesin, Methamphetamine (Desoxyn), Methylcarbamol, Naproxen, Nicotine, Phenacetin, Phenmetrazine, Phenobarb, Pentolamine, Raulwolfia, Reserpine, Robaxin, Valium (Diazepam) Foods: Avocados, Bananas, Egg plant, Plums, Pineapple, Tomatoes and Walnuts
Specimens collected between 22-26 hours will be accepted as 24 hour specimens. Anything less than 22 hours or greater than 26 hours will be ordered as a "Random" specimen and should include a Period and Volume measurement.
CPT Codes
83497
Specimen Stability
Stability Comments: Promptly freeze specimens after processing.
Stability
Refrigerated Stability: 7 days
Method
High Performance Liquid Chromatography
Notes
Analytical Time: 2-4 days
Alias
5-HIAA (5-Hydroxyindolacetic Acid), 5-OH-Indoleacetic Acid, Carcinoid Syndrome, HIAA (Hydroxyindoleacetic Acid), Serotonin Metabolite