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Test Code LAB352 5-Hydroxyindoleacetic Acid (HIAA), Urine

Sunquest ordering code

U5HAA

PERFORMING SITE

Pathology Laboratory

SPECIMEN COLLECTION

Container/Tube Type: 24 hour urine collection jug

Collection Information: 24-hour. 24-hour specimens should be refrigerated during collection. Random specimens can be analyzed, but reference ranges have not been established.

Transport Information: Entire Specimen

Remarks: Patients should abstain, if possible, from foods, medications, over-the-counter drugs, and herbal remedies for at least 72 hours prior to the test. 24-hour collections are generally recommended, but random collections may also be used. Refrigeration is the most important aspect of specimen preservation. Foods and medications that are associated with altered Urinary HIAA results: Decreased Results: Aspirin, Chlorpromazine(Thorazine), Corticotropin, Dihydroxyphenylacetic, Ethanol, Gentisic acid, Homogentisic acid, Hydrazine derivatives, Imipramine(Tofranil), Isocarboxazid(Marplan), Keto acids, Levodopa, Mao inhibitors, Methenamine, Methyldopa (Aldochlor), Phenothiazines(Compazine), Perchlorperazine, Promazine, Promethazine. Increased Results : Acetaminophen, Acetanilid, Caffeine, Coumaric acid, Ephedrine, Fluoracil, Glycerol Guaiacolate (Guaifenesin), Melphalin (Alkeran), Mephenesin, Methamphetamine (Desoxyn), Methylcarbamol, Naproxen, Nicotine, Phenacetin, Phenmetrazine, Phenobarb, Pentolamine, Raulwolfia, Reserpine, Robaxin, Valium (Diazepam) Foods: Avocados, Bananas, Egg plant, Plums, Pineapple, Tomatoes and Walnuts

Specimens collected between 22-26 hours will be accepted as 24 hour specimens.  Anything less than 22 hours or greater than 26 hours  will be ordered as a "Random" specimen and should include a Period and Volume measurement.

CPT Codes

83497

Specimen Stability

Stability Comments: Promptly freeze specimens after processing.

Stability

Refrigerated Stability: 7 days

Method

High Performance Liquid Chromatography

Notes

Analytical Time: 2-4 days

Alias

5-HIAA (5-Hydroxyindolacetic Acid), 5-OH-Indoleacetic Acid, Carcinoid Syndrome, HIAA (Hydroxyindoleacetic Acid), Serotonin Metabolite