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Test Code LAB1202 Hypersensitivity Pneumonitis Panel, Immunoglobulin G, Serum

Additional Codes

SQ:BHYPSM


Ordering Guidance


This is a panel of tests which includes serology for: Alternaria tenuis/alternata, Aspergillus fumigatus, Aureobasidium pullulans, Laceyella sacchari, Micropolyspora faeni, Penicillium chrysogenum/notatum, Phoma betae, and Trichoderma viride. If only Aspergillus fumigatus is requested, order SASP / Aspergillus fumigatus, IgG Antibodies, Serum.



Specimen Required


Container/Tube: Sarstedt Aliquot Tube, 5 mL (T914)

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL Serum

Collection Information: Centrifuge and aliquot serum into a plastic vial.


Secondary ID

623579

Useful For

Evaluation of patients suspected of having hypersensitivity pneumonitis induced by exposure to Alternaria tenuis/alternata, Aspergillus fumigatus, Aureobasidium pullulans, Laceyella sacchari, Micropolyspora faeni, Penicillium chrysogenum/notatum, Phoma betae, and Trichoderma viride

Method Name

Fluorescence Enzyme Immunoassay (FEIA)

Reporting Name

Hypersensitivity Pheum Panel,IgG, S

Specimen Type

Serum

Specimen Minimum Volume

Serum: 0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Alternaria alternata, IgG antibody: ≤19.0 mg/L

Aspergillus fumigatus, IgG antibody: ≤102.0 mg/L

Aureobasidium pullulans, IgG antibody: ≤16.0 mg/L

Laceyella sacchari, IgG antibody: ≤45.0 mg/L

Micropolyspora faeni, IgG antibody: ≤6.0 mg/L

Penicillium chrysogenum, IgG antibody: ≤94.0 mg/L

Phoma betae, IgG antibody: ≤16.0 mg/L

Trichoderma viride, IgG antibody: ≤16.0 mg/L

Method Description

The Phadia ImmunoCAP System-specific IgG-fluorescence enzyme immunoassay (FEIA) provides an in vitro method for measuring the levels of circulating specific IgG antibodies in human blood samples. Specific IgG from the patient's serum reacts with the antigen of interest, which is covalently coupled to an ImmunoCAP. After washing away nonspecific IgG, enzyme-labeled anti-IgG antibodies are added to form a complex. After incubation, unbound enzyme anti-IgG is washed away and the bound complex is then incubated with a developing agent. After stopping the reaction, the fluorescence of the eluate is measured. The fluorescence is proportional to the amount of specific IgG that is present in the patient's sample (ie, the higher the fluorescence value, the more specific IgG antibody is present).(Package insert: Phadia AB, Uppsala, Sweden 2009)

Day(s) Performed

Monday through Friday

Report Available

2 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86001 x 8

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BHYPS Hypersensitivity Pheum Panel,IgG, S 35577-6

 

Result ID Test Result Name Result LOINC Value
BH01 Alternaria alternata, IgG Ab 26951-4
BH02 Aspergillus fumigatus, IgG Ab 26954-8
BH03 Aureobasidium pullulans, IgG Ab 26955-5
BH04 Laceyella sacchari, IgG Ab 105270-3
BH05 Micropolyspora faeni, IgG Ab 26948-0
BH06 Penicillium chrysogenum, IgG Ab 26957-1
BH07 Phoma betae, IgG Ab 35551-1
BH08 Trichoderma viride, IgG Ab 49687-7
BH09 Hypersensitivity Interpretation 69048-7