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Test Code Epic LAB792 Diphtheria/Tetanus Antibody Panel, Serum

Additional Codes

SQ code TDABM

Mayo code DTABS

Reporting Name

Diphtheria/Tetanus Ab Panel, S

Specimen Type

Serum

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Assessing antibody response to tetanus and diphtheria toxoid vaccines, which should be performed at least 3 weeks after immunization

 

Aiding in the evaluation of immunodeficiency

 

This test should not be used to diagnose tetanus infection


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.8 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 30 days
  Frozen  30 days

Reference Values

DIPHTHERIA TOXOID IgG ANTIBODY

Vaccinated: Positive (≥0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

 

TETANUS TOXOID IgG ANTIBODY

Vaccinated: Positive (≥0.01 IU/mL)

Unvaccinated: Negative (<0.01 IU/mL)

Reference values apply to all ages.

Day(s) Performed

Monday through Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86317 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
DTABS Diphtheria/Tetanus Ab Panel, S 101791-2

 

Result ID Test Result Name Result LOINC Value
TETG Tetanus IgG Ab 26643-7
DIPG Diphtheria IgG Ab 45166-6
DEXDP Diphtheria IgG Value 48654-8
DEXTG Tetanus IgG Value 53935-3

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject
Heat Inactivated specimen Reject

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Profile Information

Test ID Reporting Name Available Separately Always Performed
DIPGS Diphtheria Toxoid IgG Ab, S Yes Yes
TTIGS Tetanus Toxoid IgG Ab, S Yes Yes

Method Description

The Anti-Diphtheria Toxoid enzyme-linked immunosorbent assay (ELISA) and Anti-Tetanus Toxoid ELISA provide quantitative in vitro assays for detection of human IgG-class antibodies to diphtheria and tetanus toxoid, respectively.

 

The test kits contain reagent wells coated with either diphtheria or tetanus toxoid. In the first reaction step, diluted patient samples are incubated in the wells. In the case of positive samples, specific IgG antibodies will bind to the antigens. To detect the bound antibodies, a second incubation is carried out using an enzyme-labeled antihuman IgG (enzyme conjugate), catalyzing a color reaction.(Unpublished Mayo method)

Report Available

Same day/1 to 4 days

Forms

If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.

Secondary ID

36670