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Test Code Epic LAB379 Cocaine and Metabolite Confirmation, Random, Urine

Additional Codes

SQ code COKEUM

Mayo code COKEU

Reporting Name

Cocaine and metabolite Conf, U

Specimen Type

Urine

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Detecting and confirming drug abuse involving cocaine

 

This test is not intended for employment-related testing.


Ordering Guidance


1. For situations where chain of custody is required, a Chain-of-Custody Kit (T282) is available. For chain-of-custody testing, order COKEX / Cocaine and Metabolite Confirmation, Chain of Custody, Random, Urine.

2. Additional drug panels and specific requests are available. Call 800-533-1710 or 507-266-5700.

3. If urine creatinine is required or adulteration of the sample is suspected, order ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Urine Tubes, 10 mL (T068)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: 10-mL urine tube

Specimen Volume: 10 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.


Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reference Values

Negative

Positive results are reported with a quantitative gas chromatography mass spectrometry (GC-MS) result.

Cutoff concentrations:

COCAINE BY GC-MS

<50 ng/mL

 

BENZOYLECGONINE BY GC-MS

<50 ng/mL

Day(s) Performed

Monday, Wednesday, Thursday, Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80353

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
COKEU Cocaine and metabolite Conf, U 53747-2

 

Result ID Test Result Name Result LOINC Value
2922 Cocaine-by GC/MS 20519-5
2902 Benzoylecgonine-by GC/MS 16226-3
20671 Cocaine Interpretation 69050-3
28080 Chain of Custody 77202-0

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Gas Chromatography Mass Spectrometry (GC-MS) Confirmation with Quantitation

Report Available

2 to 5 days

Secondary ID

9286

Method Description

To accommodate the need to confirm specifically the presence of cocaine in urine, Mayo Clinic Laboratories offers a single test to identify cocaine and its principal metabolite, benzoylecgonine, by using gas chromatography mass spectrometry.(Chinn DM, Crouch DJ, Peat MA, et al. Gas chromatography-chemical ionization mass spectrometry of cocaine and its metabolites in biological fluids. J Anal Toxicol 1980;4:37-42; Rosado T, Goncalves A, Margalho C, Barroso M, Gallardo E. Rapid analysis of cocaine and metabolites in urine using microextraction in packed sorbent and GC/MS. Anal Bioanal Chem. 2017;409(8):2051-2063. doi:10.1007/s00216-016-0152-2)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.