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Test Code Epic LAB191 Haloperidol, Serum

Additional Codes

SQ code HALOM

Mayo code HALO

Reporting Name

Haloperidol, S

Specimen Type

Serum Red

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Useful For

Optimizing haloperidol dosage

 

Monitoring patient compliance

 

Assessing toxicity


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Haloperidol:

5-17 ng/mL

 

Reduced Haloperidol:

10-80 ng/mL

Day(s) Performed

Tuesday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

80173

LOINC Code Information

Test ID Test Order Name Order LOINC Value
HALO Haloperidol, S 87550-0

 

Result ID Test Result Name Result LOINC Value
80339 Haloperidol, S 3669-9
169 Reduced Haloperidol 38364-6

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Method Description

Haloperidol and reduced haloperidol, its major metabolite, are extracted from serum utilizing protein precipitation and diluted by the addition of internal standard (haloperidol-d4 and reduced haloperidol-d4). Analysis of the supernate is performed on a liquid chromatography tandem mass spectrometry system.(Unpublished Mayo method)

Report Available

2 to 8 days

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.

Secondary ID

80339