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HelpTest Code Epic LAB1209 Q Fever IgM and IgG, Titer, Serum
Additional Codes
SQ code QFABM
Mayo code QFP
Reporting Name
Q Fever IgM/IgG, Titer, SSpecimen Type
SerumPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Diagnosis of Coxiella burnetii, the causative agent of Q fever
Testing Algorithm
For more information see Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology.
Ordering Guidance
Specimen Required
Only orderable as a reflex. For more information see QFEVR / Q Fever Antibody Screen with Titer Reflex, Serum.
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 7 days |
Reference Values
Only orderable as a reflex. For more information see QFEVR / Q Fever Antibody Screen with Titer Reflex, Serum.
Q fever phase I antibody, IgG
<1:16
Q fever phase II antibody, IgG
<1:16
Q fever phase I antibody, IgM
<1:16
Q fever phase II antibody, IgM
<1:16
Reference values apply to all ages.
Day(s) Performed
Monday through Saturday
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86638 x 4
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| QFP | Q Fever IgM/IgG, Titer, S | 77175-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80965 | Q Fever Phase I Ab, IgG | 34716-1 |
| 24011 | Q Fever Phase II Ab, IgG | In Process |
| 81115 | Q Fever Phase I Ab, IgM | 9710-5 |
| 24009 | Q Fever Phase II Ab, IgM | 9711-3 |
| 24010 | Interpretation | 69048-7 |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Method Name
Only orderable as a reflex. For more information see QFEVR / Q Fever Antibody Screen with Titer Reflex, Serum.
Indirect Immunofluorescence
Method Description
An indirect immunofluorescence test is used for the measurement of IgM and IgG antibodies to Coxiella burnetii. Specific antibodies present in the serum of the patient react with rickettsial cells that have been previously fixed on a glass microscope slide. Fluorescein-labeled antihuman IgG or IgM conjugate is used to stain specific antibody bound to the substrate cells. The slides are examined with a fluorescence microscope for characteristic, apple-green fluorescence of the infected cell.(Edligner B. Immunofluorescence serology. A tool for prognosis of Q fever. Diagn Microbiol Infect Dis. 1985;3[4]:343-351; package inserts: Q fever IFA IgG. Focus Diagnostics, Inc; 12/2022; Q fever IFA IgM. Focus Diagnostics, Inc; 12/2022)