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HelpTest Code Epic LAB1110 Vitamin K1, Serum
Additional Codes
SQ code VITKMM
Mayo code VITK1
Reporting Name
Vitamin K1, SSpecimen Type
SerumPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Useful For
Assessing circulating vitamin K1 concentration
Specimen Required
Patient Preparation: Fasting overnight (12-14 hours) (infants-collect prior to next feeding).
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 30 days | |
| Ambient | 30 days | ||
| Frozen | 30 days |
Reference Values
<18 years: Not established
≥18 years: 0.10-2.20 ng/mL
Day(s) Performed
Monday through Friday
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
84597
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| VITK1 | Vitamin K1, S | 9622-2 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 62167 | Vitamin K1, S | 9622-2 |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Secondary ID
42364Method Description
Deuterated stable isotope (vitamin K1-d7) is added to a serum sample as an internal standard. Protein is precipitated from the mixture by the addition of ethanol. Vitamin K1 and internal standard are extracted from the resulting supernatant by solid-phase extraction. Vitamin K1 and internal standard are then separated utilizing high-throughput liquid chromatography with analysis on a tandem mass spectrometer equipped with a heated nebulizer ion source using multiple-reaction monitoring.(Unpublished Mayo method)
Report Available
2 to 5 daysForms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.